About Us

AAVnerGene is a leading biotech company specializing in the development of advanced gene therapy technologies utilizing the AAV platform. Situated in Rockville, Maryland, our state-of-the-art facilities span over 10,000 square feet, housing dedicated spaces for research and development as well as production capabilities. With a leadership team boasting over two decades of experience in the field of AAV gene therapy, along with numerous publications and patents, we are at the forefront of innovation.

Our objective is to enhance the accessibility of gene therapy by addressing the bottlenecks in AAV gene therapy. 

We have introduced groundbreaking AAV production systems known as AAVone and AAVdual. AAVone system employs just a single plasmid for AAV packaging, resulting in a 2-4 fold increase in packaging efficiency. Conversely, the AAVdual system utilizes two plasmids for AAV vector packaging, simultaneously elevating production efficiency while preserving the flexibility to generate various AAV serotypes.   

We’ve pioneered the ATHENA platform, encompassing ATHENA IATHENAII, and ATHENA III, to streamline the process of comparing, selecting, and evolving AAV capsids. ATHENA I is a recognized capsid library designed for the purpose of comparing and selecting the most promising AAV serotypes or variants. ATHENA II, on the other hand, is a random peptide insert library tailored for the development of novel AAV capsids with specific functionalities. Lastly, ATHENA III serves as a rational DNA shuffling library, enabling the creation of innovative hybrid AAV capsids through a deliberate approach.

As scientists ourselves, we are fueled by a profound passion to empower fellow researchers in achieving breakthroughs using the AAV platform for gene therapy. We take pride in providing a wide range of AAV products and comprehensive AAV services in AAV design, AAV packaging, AAV analysis, AAV optimization, and  AAV capsid library design, construction, production, screening and evolution, to both academic institutions and companies. By collaborating with us, you gain access to our expertise and cutting-edge technologies to propel your research and therapeutic endeavors forward.

Together, let us pave the way for a future where gene therapy becomes accessible and transformative for all. 

Contact us today to explore the vast possibilities of the AAV platform and embark on a journey of scientific discovery and impact.

We warmly welcome potential collaborators and investors to join us on this transformative journey. For inquiries and further information, kindly reach out to our esteemed President and CEO, Mr. Daozhan Yu, at daozhan.yu@aavnergene.com. Together, we can drive the future of gene therapy and bring meaningful impact to patients worldwide.

Core Values of AAVnerGene


Our passion is to solve the bottleneck problems in AAV gene therapy and find more and better cures for all the patients. We believe that hard core technologies are the key to achieve it. AAVnerGene develops novel AAV vectors, methods and strategies that can efficiently produce, deliver and express high quality vectors into specific cells. Our goal is to increase AAV gene therapy efficacy and decrease the cost, making it accessible and affordable to patients.


AAVnerGene provides you consistent, high quality, affordable AAV vectors. Customers can compare different batch AAV vectors which are ordered from our company.  AAVnerGene offers AAV barcoding technology and high complexity capsid library. Customers can directly select and develop their own novel AAV vectors for gene delivery and gene therapy.

Commitment to customers

Customer satisfaction is a number one priority for AAVnerGene. Our company is dedicated to providing outstanding customer service, listening to customer requests and being reachable at all times. This has enabled us to build long-lasting relationships with our clients and partners.


When we use the word ownership, we are referring to a culmination of personal accountability, a culture of organizational responsibility, and owning the outcomes and consequences of our actions. Taking ownership means that we hold ourselves accountable in all our operations and efforts. 


The strength of our team does not only lie in our combined experience and expertise but our ability to trust each other, no matter what the circumstances. We know that our best work is not produced by individuals but by enjoying collaboration as a team and supporting each other every day. This team mentality also extends to our clients as we approach every business relationship as a partnership and work collaboratively with each other to meet our goals.


We are constantly aiming to grow both as individuals and as a company. We believe that the journey of education is a lifelong pursuit, and that this kind of lifelong learning is what will continue to push us forward as a company