Welcome to Partner with AAVnerGene. Revolutionize Gene Therapy by Advancing AAV Technology.
AAV Products
At AAVnerGene, we specialize in advancing the frontiers of gene therapy through cutting-edge AAV technologies, services and products. Our comprehensive AAV products are tailored to meet the diverse needs of researchers, clinicians, and biotechnology companies.
AAV Plasmids
AAV plasmids for different production systems (AAVone, AAVdual, and AAVtri) and
AAV barcode plasmids for capsid evaluation
AAV Viruses
High-quality premade AAV vectors, tools, biosensors (serotypes, promoters, and transgenes)
for gene delivery and gene therapy
AAV Biosensors
Constitutive, Cre-dependent
or Flp-dependent; Sensitive, cell-type–specific, and longitudinal tracking of biological processes
AAV References
Three well-characterized AAV reference materials (full AAV particles, truly-empty AAV particles
and byproduct empty AAV particles) for your needs
AAV Capsid Kits
AAV capsid barcode kits and AAV serotype testing kits to evaluate & select the best AAV serotypes and AAV variants for specific applications
AAV Capsid Libraries
Highly complexity NNK7 insertion capsid libraries (different serotypes and variable regions) for AAV capsid engineering and evolution
AAV Reagents
PEIone Transfection Reagent and ENone AAV Production Enhancer provide a complete solution for efficient, high-yield, and high-quality AAV manufacturing
AAV ACTOne GPCR Assay Kits
Live-cell-based cAMP biosensor systems for rapid and high-throughput functional screening of GPCRs
AAV Services
Our commitment to quality, precision, and collaboration ensures that your projects are supported at every stage of development. Explore our six core services, designed to accelerate your journey from concept to breakthrough.
AAV Vector
Design
AAV vector design and construction; AAV serotypes, promoter, and AAV production systems; AAV-shRNA/sgRNA design and screening
AAV Packaging Services
Made in USA;
High-quality;
Fast turnaround;
Affordable prices;
Friendly custom services;
~ 20 year AAV experience
AAV Characterization
Comprehensive AAV analytical services (capsid, genome, potency and safety) for both academia and industry
AAV Library
Services
AAV library design, construction, production and evolution; AAV capsid library; AAV promoter/enhancer library; AAV-shRNA/sgRNA library
AAV Capsid Development
Development of novel AAVs with ATHENA-I, ATHENA-II, ATHENA-III platform use both
in vitro (cell lines, primary cells, organoids) and in vivo models
AAV Experiment Services
Provide tailored services for all stages; AAV validation and biodistribution; AAV Nab Testing; AAV genome optimization; AAV Productivity test;
AAV potency and rcAAV assays
AAV Technologies
At AAVnerGene, we lead the way in transformative gene therapy solutions through state-of-the-art technological platforms. Explore our four flagship technologies: Novel AAV capsids, AAVone single-plasmid AAV production system, AAV-Q AAVTCID50 /rcAAV assays, and ATHENA capsid engineering platform.
- AAV-ChP – Specifically targets the choroid plexus following ICV or IT administration, enabling targeted gene delivery for CNS diseases.
- AAV-ShD – Efficiently targets lung macrophages following IV administration, making it well suited for pulmonary and immune-related therapeutic applications.
- AAV-rT – Efficiently transduces resting T cells, providing a promising platform for in vivo CAR-T cell therapies.
- Use 1 plasmid instead of 3 plasmids for AAV production;
- Achieves 2- to 4-fold higher productivity vs AAVtri;
- >70% full-particle ratio across AAV serotypes;
- Generate >5e15 VG/L titers for AAV9 in HEK 293 cells;
- Reduce consumable costs up to 78%;
- Low plasmid-related impurities to less than 2.5%;
- Supported with high efficient PEIone, ENone and HEK293one
- Three cell lines, two assays and one Rd-Ad vector;
- Ultra-sensitive: Detects a single-copy.
- Quick results: Turnaround within one week.
- Broadly compatible: works with most AAV serotypes.
- Safe design: Uses replication-defective Ad5.
- Cost-efficient: streamlined qPCR workflow.
- Reliable & robust: Low variability and high reproducibility
- ATHENA-I Barcoded AAV Capsid Library enables high-throughput selection of AAV capsids for specific target tissues and cell types
- ATHENA-II random peptide insertion library with high complexity creates novel capsids for capsid evolution for different targets
- ATHENA-III combines the benefits of different AAV properties;
- ATHENA Platforms allow users to efficiently evaluate, evolve, and create AAV variants tailored for specific therapeutic applications
Partner with AAVnerGene
At AAVnerGene, we believe the next generation of gene therapies will be built through strong scientific partnerships. We welcome collaboration with academic laboratories, biotechnology companies, pharmaceutical organizations, research institutes, hospitals, investors, and manufacturing partners working across the AAV field.
Our team has extensive experience in choroid plexus (ChP) targeting gene therapy, AAV production, capsid engineering, vector design, process development, analytical characterization, and gene therapy research. Whether you are developing a new therapeutic program, improving an existing vector, evaluating a novel capsid, or addressing a manufacturing challenge, we are ready to explore how our technologies and expertise can support your goals.
Why AAVnerGene
Tailored high-quality AAV solutions with expert collaboration.
AAV Expertise
We offer end-to-end solutions from vector design and packaging to capsid engineering and optimization. Our deep expertise ensures reliable, high-quality outcomes tailored to your gene therapy needs
Customizable & Innovative Solutions
We tailor GOI solutions, capsid library construction, and selection to meet unique client needs, delivering innovative solutions for complex projects
Rigorous Quality Standards
Our commitment to excellence ensures that every project undergoes stringent quality control, delivering consistent, reproducible results that comply with the highest industry standards
Collaborative Approach
We prioritize client partnerships. Our expert consultation services ensure seamless collaboration and a thorough understanding of your project goals for both success
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