AAV Capsid Libraries
AAV Capsid Libraries are random peptide insertion libraries developed using our ATHENA-II platform, designed to evolve novel AAV capsids with tissue-specific tropism. In the premade libraries, the CAP gene with random peptides is driven by a CAG/P40 hybrid promoter—the P40 promoter is utilized during AAV production to drive CAP expression, while the CAG promoter is used for CAP expression in targeted cells or tissues.
AAVnerGene offers AAV Capsid Libraries with various serotypes, insertions in key variable regions (VR-VIII and VR-IV), and peptide lengths ranging from NNK7 to NNK9. Each library has a complexity exceeding 1e9. These libraries are produced under a 200 copies per cell condition and are purified through two rounds of CsCl ultracentrifugation. Researchers can use these libraries to evolve novel AAV capsids at both the DNA and RNA levels, enabling precise control over capsid design and tissue-specific targeting.
| Name | SKU | Price | Buy |
|---|---|---|---|
| AAV9 Capsid Libraries | DB005-AAV9 | Price range: $9,999.00 through $69,999.00 | |
| AAV8 Capsid Libraries | DB005-AAV8 | Price range: $9,999.00 through $69,999.00 | |
| AAV1 Capsid Libraries | DB005-AAV1 | Price range: $9,999.00 through $69,999.00 | |
| AAV2 Capsid Libraries | DB005-AAV2 | Price range: $9,999.00 through $69,999.00 | |
| AAV6 Capsid Libraries | DB005-AAV6 | Price range: $9,999.00 through $69,999.00 | |
| AAV3B Capsid Libraries | DB005-AAV3B | Price range: $9,999.00 through $69,999.00 | |
| AAVrh.74 Capsid Libraries | DB005-AAVrh.74 | Price range: $9,999.00 through $69,999.00 | |
| AAV5 Capsid Libraries | DB005-AAV5 | Price range: $9,999.00 through $69,999.00 | |
| AAV7 Capsid Libraries | DB005-AAV7 | Price range: $9,999.00 through $69,999.00 | |
| AAVrh.10 Capsid Libraries | DB005-AAVrh.10 | Price range: $9,999.00 through $69,999.00 |