AAV as a Tool for Neuroscience: Unlocking the Brain’s Secrets
In the past two decades, adeno-associated virus (AAV) has become one of the most powerful tools (AAV tools) in neuroscience, including for the delivery of AAV biosensors. Its ability to…
Category AAV Biology
Read MoreAAV as a Tool for Neuroscience: Unlocking the Brain’s Secrets
List of AAV capsids
A multitude of AAV capsids have been documented, encompassing widely recognized AAV serotypes (AAV1-13), as well as custom-engineered capsids and naturally occurring capsids isolated from various species such as humans…
ssAAV, scAAV, and Packaging Capacity
Adeno-associated viruses (AAVs) can be engineered in two different forms: single-stranded AAV (ssAAV) and self-complementary AAV (scAAV). These forms differ in their genome structure and mechanism of transgene expression, and…
AAV ITR integrity
The Inverted Terminal Repeats (ITRs) in adeno-associated virus (AAV) vectors are essential for the replication, packaging, and integration of the viral genome. Ensuring the stability of ITRs is crucial for…
Inverted Terminal Repeat of AAV
Read MoreInverted Terminal Repeat of AAVOverview of AAV biology
Adeno-associated viruses(AAVs) are small, non-enveloped viruses that belong to the family Parvoviridae[1,2]. They are widely used as gene delivery vectors for various research and therapeutic applications due to their non-pathogenic…