AAV References
AAV References
In the rapidly evolving field of gene therapy, the reliability and accuracy of research depend significantly on the use of high-quality reference materials. Both researchers and regulatory bodies like the FDA emphasize the importance of well-characterized AAV reference materials. AAVnerGene provides two types of AAV reference materials: AAV References (Full) and AAV References (Empty).
AAV References at AAVnerGene
AAV references (Full) and AAV references (Byproduct-Empty) are generated using the AAVone system, with the corresponding pAAVone plasmids carrying a 2.8 kb AAV-CMV-SV40I-EGFP-WPRE-hGHpolyA genome. AAV references (Truly-Empty) are produced by transfection of a single mini-pHelper-AAV plasmid with the corresponding serotypes. AAV reference materials are available for various serotypes, including AAV1, AAV2, AAV5, AAV6, AAV8, AAV9, AAVrh.10, and AAVrh.74. AAV references with other serotypes and genomes are available upon request.
| AAV References | Serotype | Genome | Production Plasmids |
| AAV References (Full) |
AAV1, AAV2, AAV5, AAV6, AAV8, AAV9, AAVrh.10, AAVrh.74 | Full of AAV-CMV-SV40I-EGFP-WPRE-hGHpolyA-2.8kb | pAAVone-AAVs-CMV-EGFP-2.8kb |
| AAV References (Truly-Empty) |
AAV1, AAV2, AAV5, AAV6, AAV8, AAV9, AAVrh.10, AAVrh.74 | No | mini-pHelper-AAVs |
| AAV References (Byproduct-Empty) |
AAV1, AAV2, AAV5, AAV6, AAV8, AAV9, AAVrh.10, AAVrh.74 | Partial of AAV-CMV-SV40I-EGFP-WPRE-hGHpolyA-2.8kb | pAAVone-AAVs-CMV-EGFP-2.8kb |
AAV Reference (Full)
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AAV References (Truly-Empty)
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AAV References (Byproduct-Empty)
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AAVnerGene offers high quality, short turnaround, high efficiency custom AAV packaging services with our unique single-plasmid AAV production system (AAVone), dual-plasmid AAV production system(AAVdual) or improved triple-plasmid system(AAVtri) with our mini-pHelper.
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