Neurotransmitters and neuromodulators Neurotransmitters and neuromodulators are chemical messengers that play essential roles in signal transmission within neural circuits. Neurotransmitters are released from the axon terminals of presynaptic neurons and…
In the past two decades, adeno-associated virus (AAV) has become one of the most powerful tools (AAV tools) in neuroscience, including for the delivery of AAV biosensors. Its ability to…
Mass Photometry Mass photometry is a cutting-edge technique used for analyzing the mass of individual molecules in solution by measuring the light scattering when they land on a sensor surface,…
The sequence of the promoter region controls the binding of the RNA polymerase and transcription factors, therefore promoters play a large role in determining where and when your gene of…
Adeno-associated viruses (AAVs) can be engineered in two different forms: single-stranded AAV (ssAAV) and self-complementary AAV (scAAV). These forms differ in their genome structure and mechanism of transgene expression, and…
The Inverted Terminal Repeats (ITRs) in adeno-associated virus (AAV) vectors are essential for the replication, packaging, and integration of the viral genome. Ensuring the stability of ITRs is crucial for…
An AAV plasmid backbone is a DNA construct that serves as the template for creating AAV vectors in the laboratory. It contains essential elements required for the replication, packaging, and…
Adeno-associated viruses (AAVs) can be engineered in two different forms: single-stranded AAV (ssAAV) and self-complementary AAV (scAAV). These forms differ in their genome structure and mechanism of transgene expression, and…
